Licorice Root

Common name

licorice, liquorice, sweet root, gan cao, gan-zao, Chinese licorice

ID

HD0046

Scientific name of the plant

Glycyrrhiza glabra L. and/or Glycyrrhiza inflata Bat. and/or Glycyrrhiza uralensis Fisch.

Anatomical part for use

root, stem

Human use

Cough and cold

Summary

Liquorice (British English) or licorice (American English) ( LIK-ər-is(h), ) is the common name of Glycyrrhiza glabra, a flowering plant of the bean family Fabaceae, from the root of which a sweet, aromatic flavouring can be extracted. The liquorice plant is a herbaceous perennial legume native to Western Asia, North Africa and southern Europe. It is not botanically closely related to anise or fennel, which are sources of similar flavouring compounds. (Another such source, star anise, is even more distant from anise and fennel than liquorice is, despite its similar common name.) Liquorice is used as a flavouring in candies and tobacco, particularly in some European and West Asian countries. Liquorice extracts have been used in herbalism and traditional medicine. Excessive consumption of liquorice (more than 2 mg/kg per day of pure glycyrrhizinic acid, a liquorice component) may result in adverse effects, such as hypokalemia, increased blood pressure, muscle weakness, and death.

Evidence Level

Level 1 (Individual reports from one medical center)

Hepatotoxicity reports in literature

  • Traditional Chinese medicine causing hepatotoxicity in patients with chronic hepatitis B infection: a 1-year prospective study : (Source)

Hepatotoxicity Description

N/A

Relevant Public Information

Wiki
EMA
NIH MedlinePlus
NIH ODS
Nature Medicines